Plant Transcription Factor Database
Previous version: v3.0
Elaeis guineensis
HSF Family
Species TF ID Description
XP_010907976.1HSF family protein
XP_010908034.1HSF family protein
XP_010908044.1HSF family protein
XP_010908496.1HSF family protein
XP_010909933.1HSF family protein
XP_010911318.1HSF family protein
XP_010912232.1HSF family protein
XP_010913096.1HSF family protein
XP_010913097.1HSF family protein
XP_010913099.1HSF family protein
XP_010913100.1HSF family protein
XP_010915288.1HSF family protein
XP_010915289.1HSF family protein
XP_010915439.1HSF family protein
XP_010916238.1HSF family protein
XP_010916239.1HSF family protein
XP_010916598.1HSF family protein
XP_010917615.1HSF family protein
XP_010918529.1HSF family protein
XP_010919270.1HSF family protein
XP_010922077.1HSF family protein
XP_010924707.1HSF family protein
XP_010924752.1HSF family protein
XP_010925572.1HSF family protein
XP_010926094.1HSF family protein
XP_010931521.1HSF family protein
XP_010933440.1HSF family protein
XP_010933854.1HSF family protein
XP_010934470.1HSF family protein
XP_010935646.1HSF family protein
XP_010939421.1HSF family protein
XP_010940507.1HSF family protein
XP_010940869.1HSF family protein
XP_010943066.1HSF family protein
XP_010943094.1HSF family protein
XP_010943416.1HSF family protein
HSF Family Introduction

Heat stress transcription factors (Hsfs) are the major regulators of the plant heat stress (hs) response. Sequencing of the Arabidopsis genome revealed the existence of 21 open-reading frames (ORFs) encoding putative Hsfs assigned to classes A-C. Here we present results of a functional genomics approach to the Arabidopsis Hsf family focused on the analysis of their C-terminal domains (CTDs) harboring conserved modules for their function as transcription factors and their intracellular localization. Using reporter assays in tobacco protoplasts and yeast as well as glutathione-S-transferase (GST) pull-down assays, we demonstrate that short peptide motifs enriched with aromatic and large hydrophobic amino acid (aa) residues embedded in an acidic surrounding (AHA motifs) are essential for transcriptional activity of class A Hsfs. In contrast to this, class B and C Hsfs lack AHA motifs and have no activator function on their own. We also provide evidence for the function of a leucine (Leu)-rich region centered around a conserved QMGΦL motif at the very C-terminus as a nuclear export signal (NES) of class A Hsfs. Sequence comparison indicates that the combination of a C-terminal AHA motif with the consensus sequence FWxxF/L,F/I/L as well as the adjacent NES represents a signature domain for plant class A Hsfs, which allowed to identify more than 60 new Hsfs from the expressed sequence tag (EST) database.

Kotak S, Port M, Ganguli A, Bicker F, von Koskull-Doring P.
Characterization of C-terminal domains of Arabidopsis heat stress transcription factors (Hsfs) and identification of a new signature combination of plant class A Hsfs with AHA and NES motifs essential for activator function and intracellular localization.
Plant J, 2004. 39(1): p. 98-112.
PMID: 15200645